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Potential for HIV cure beyond the state of the ART?
Medicine has long been able to guarantee HIV patients an almost normal life and now it can fully cure the virus too — but the treatment is not appropriate for all, explain ROX MIDDLETON, LIAM SHAW and JOEL HELLEWELL
COMPLEX: Watercolour and ink on paper illustration of HIV maturation. After full assembled virus particles have been released from an infected target cell (usually CD4 T cells, a type of white blood cell found in the immune system), they undergo a process of maturation in order to become fully infectious viral particles.
[David S Goodsell / Welcome Collection / Creative Commons]
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THE development of antiretroviral therapies (ART) has meant that, where available, people living with the human immunodeficiency virus (HIV) now have a normal life expectancy.
Yet despite this achievement, ART is not a cure for HIV and people living with HIV need to keep taking ART for the rest of their life to prevent the development of acquired immune deficiency syndrome (Aids).
As of this moment, two people have been — or at least appear to have been — completely cured of HIV infection, the virus was eradicated from their body and they no longer needed to take ART.
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